Kumar, Y. Pavan (2016) Guanosine Derivatives for the Selective G-quadruplex Recognition and Synthetic Ion Channel Formation. PhD thesis, Indian Institute of Science Education and Research Kolkata.
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PDF (PhD thesis of Y. Pavan Kumar)
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Abstract
This thesis “Guanosine Derivatives for the Selective G-quadruplex Recognition and Synthetic Ion Channel Formation” describes synthesis of mono- and di-guanosine derivatives using a modular synthetic approach using click chemistry. This thesis comprises two chapters. Chapter 1 describes design and synthesis of guanosine derivatives linked with fluorescent probes (dansyl and anthracene) using Click-Chemistry for the detection of G-quadruplex structures. Chapter 2 describes synthesis of diguanosine derivatives using Click-Chemistry which can self-assemble to form synthetic ion channels across a biological membrane.
| Item Type: | Thesis (PhD) |
|---|---|
| Additional Information: | Supervisor: Dr. Jyotirmayee Dash and Dr. Balaram Mukhopadhyay |
| Uncontrolled Keywords: | Biological Membrane; Click Chemistry; Di-guanosine Derivatives; Fluorescent Probes; Guanosine Derivatives; Modular Synthetic Approach; Mono-guanosine Derivatives; Synthetic Ion Channel |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Department of Chemical Sciences |
| Depositing User: | IISER Kolkata Librarian |
| Date Deposited: | 29 Aug 2016 10:09 |
| Last Modified: | 29 Aug 2016 10:10 |
| URI: | http://eprints.iiserkol.ac.in/id/eprint/494 |
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