Synthesis, characterization and protein interaction study of mannose polymer

Kanjilal, Pintu (2018) Synthesis, characterization and protein interaction study of mannose polymer. Masters thesis, Indian Institute of Science Education and Research Kolkata.

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A 1,6-heptadiyne based polymer was synthesized using Hoveyda-Grubbs’ 2nd generation catalyst and post polymer modification was done to attach alkyne functionality to the polymeric backbone. Also, a azide functionalized β-D mannose was made and click reaction was performed via CuAAC to synthesize RCM-Man polymer. All respective compounds and polymers were characterized successfully. The amphiphilic RCM-Man polymer self-assembled into micelle and capsule morphologies in DMSO and water respectively. Fluorescence spectroscopy was used to study the interaction of RCM-Man polymer with Con A.

Item Type: Thesis (Masters)
Additional Information: Supervisor: Dr. Raja Shunmugam
Uncontrolled Keywords: Hoveyda-Grubbs’; Mannose Polymer; RCM-Man Polymer
Subjects: Q Science > QD Chemistry
Divisions: Department of Chemical Sciences
Depositing User: IISER Kolkata Librarian
Date Deposited: 04 Dec 2018 06:03
Last Modified: 04 Dec 2018 06:04

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