Chemical Synthesis of Biologically Active Bacterial Oligosaccharides

Pal, Debasish (2022) Chemical Synthesis of Biologically Active Bacterial Oligosaccharides. PhD thesis, Indian Institute of Science Education and Research Kolkata.

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Abstract

The thesis is divided in the following five chapters. Chapter 1 illustrates the biological significance of carbohydrates in various life processes and therapeutic uses. Chapter 2 deals with the modern glycosylation techniques for stereoselective 1,2-cis glycosides in the domain of chemical O-glycosylation. Chapter 3 details the chemical synthesis of the pentasaccharide repeating unit of the Ospecific polysaccharide from Escherichia coli O132 in the form of its 2- aminoethyl glycoside. Chapter 4 illustrates chemical synthesis of β-L-rhamnose containing pentasaccharide repeating unit of the O-specific polysaccharide from a halophilic bacterium Halomonas ventosae RU5S2EL in the form of its 2-aminoethyl glycoside. Chapter 5 demonstrates the chemical synthesis of the trisaccharide repeating unit of the Oantigen from Pseudomonas putida BIM B-1100.

Item Type: Thesis (PhD)
Additional Information: Supervisor: Prof. Balaram Mukhopadhyay
Uncontrolled Keywords: Carbohydrates; Escherichia coli; Glycosylations; Oligosaccharide; Pentasaccharide; Trisaccharide
Subjects: Q Science > QD Chemistry
Divisions: Department of Chemical Sciences
Depositing User: IISER Kolkata Librarian
Date Deposited: 30 Aug 2022 10:58
Last Modified: 30 Aug 2022 10:58
URI: http://eprints.iiserkol.ac.in/id/eprint/1160

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