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Multicomponent Functional Solids and Their Structure-property Relationship: Crystal Engineering

Ranjan, Subham (2017) Multicomponent Functional Solids and Their Structure-property Relationship: Crystal Engineering. Masters thesis, Indian Institute of Science Education and Research Kolkata.

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    Abstract

    Crystal engineering has emerged as the most advanced aspect of solid state chemistry owing to its numerous applications in diverse fields. In this context, I tried to explore the broad spectrum of crystal engineering implications in designing new solid forms with desired properties. Chapter 1 provides a brief overview about crystal engineering and its various applications. Chapter 2 describes about a crystal engineering approach to design multicomponent solid form of a poorly soluble drug, hydrochlorothiazide so as to tune its poor physicochemical properties. Chapter 3 demonstrates a study of isomorphism in multicomponent solids of mefenamic acid and tolfenamic acid and using the resulting crystal structural landscape for finding the hidden forms of the parent APIs. Chapter 4 describes about the structure-mechanical property relationship of three polymorphs of a Schiff base of isatin. Further, the thermal responses were investigated for the three polymorphs.

    Item Type: Thesis (Masters)
    Additional Information: supervisor: Dr. C Malla Reddy
    Uncontrolled Keywords: Crystal Engineering; Hydrochlorothiazide; Isatin Schiff Base; Isomorphism; Multicomponent Functional Solids; Multicomponent Solids; Mefenamic Acid; Tolfenamic Acid
    Subjects: Q Science > QD Chemistry
    Divisions: Department of Chemical Sciences
    Depositing User: IISER Kolkata Librarian
    Date Deposited: 14 Nov 2017 12:58
    Last Modified: 14 Nov 2017 12:59
    URI: http://eprints.iiserkol.ac.in/id/eprint/571

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